AAV-Directed Persistent Expression of a Gene Encoding Anti-Nicotine Antibody for Smoking Cessation-Reference-Cited by-同舟云学术

AAV-Directed Persistent Expression of a Gene Encoding Anti-Nicotine Antibody for Smoking Cessation

Published:2012-06-27 Issue:140 Volume:4 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Hicks Martin J.¹,Rosenberg Jonathan B.¹,De Bishnu P.¹,Pagovich Odelya E.¹,Young Colin N.²,Qiu Jian-ping¹,Kaminsky Stephen M.¹,Hackett Neil R.¹,Worgall Stefan¹³,Janda Kim D.⁴,Davisson Robin L.²⁵,Crystal Ronald G.¹

Affiliation:

1. Department of Genetic Medicine, Weill Cornell Medical College, New York, NY 10065, USA.

2. Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14850, USA.

3. Department of Pediatrics, Weill Cornell Medical College, New York, NY 10065, USA.

4. Departments of Chemistry and Immunology and Microbial Science, Scripps Research Institute, La Jolla, CA 92037, USA.

5. Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY 10065, USA.

Abstract

Gene therapy with an anti-nicotine monoclonal antibody limits nicotine access to the brain in mice and may be a potential therapy for cigarette addiction.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference46 articles.

1. U.S. Department of Health and Human Services Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report (Centers for Disease Control and Prevention Atlanta GA 2010) pp. 1125–1162.

2. Epidemiology of Lung Cancer: Looking to the Future

3. Relation of Cigarette Smoking to 25-Year Mortality in Middle-aged Men with Low Baseline Serum Cholesterol : The Chicago Heart Association Detection Project in Industry

4. Tobacco use in relation to COPD and asthma

5. K. Sebelius How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease: A Report of the Surgeon General (U.S. Department of Health and Human Services Atlanta GA 2010).

Cited by 46 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Optimization strategies and advances in the research and development of AAV‐based gene therapy to deliver large transgenes;Clinical and Translational Medicine;2024-03

2. Attenuating nicotine’s effects with high affinity human anti-nicotine monoclonal antibodies;PLOS ONE;2021-07-30

3. Immune to addiction: how immunotherapies can be used to combat methamphetamine addiction;Expert Review of Vaccines;2021-06-01

4. Current progress and limitations of AAV mediated delivery of protein therapeutic genes and the importance of developing quantitative pharmacokinetic/pharmacodynamic (PK/PD) models;Advanced Drug Delivery Reviews;2021-03

5. Intranasal delivery of a nicotine vaccine candidate induces antibodies in mouse blood and lung mucosal secretions that specifically neutralize nicotine;Drug Development and Industrial Pharmacy;2020-09-15