Successful Treatment of Ebola Virus–Infected Cynomolgus Macaques with Monoclonal Antibodies-Reference-Cited by-同舟云学术

Successful Treatment of Ebola Virus–Infected Cynomolgus Macaques with Monoclonal Antibodies

Published:2012-06-13 Issue:138 Volume:4 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Qiu Xiangguo¹,Audet Jonathan²,Wong Gary²,Pillet Stephane¹,Bello Alexander²,Cabral Teresa¹,Strong Jim E.¹,Plummer Frank¹,Corbett Cindy R.¹²³,Alimonti Judie B.¹²,Kobinger Gary P.¹²³

Affiliation:

1. National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba R3E 3R2, Canada.

2. Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba R3E 0J9, Canada.

3. Department of Immunology, University of Manitoba, Winnipeg, Manitoba R3E 0T5, Canada.

Abstract

Macaques survived infection with Ebola virus when treated starting at 24 hours after infection with mix of three neutralizing monoclonal antibodies.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference37 articles.

1. Ebola haemorrhagic fever: experimental infection of monkeys

2. Disease modeling for Ebola and Marburg viruses

3. Replication, Pathogenicity, Shedding, and Transmission of Zaire ebolavirus in Pigs

4. Recent advances inEbolavirusvaccine development

5. Effective Post-Exposure Treatment of Ebola Infection

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