Natural Selection in a Bangladeshi Population from the Cholera-Endemic Ganges River Delta-Reference-Cited by-同舟云学术

Natural Selection in a Bangladeshi Population from the Cholera-Endemic Ganges River Delta

Published:2013-07-03 Issue:192 Volume:5 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Karlsson Elinor K.¹²,Harris Jason B.³⁴,Tabrizi Shervin¹²,Rahman Atiqur³⁵,Shlyakhter Ilya¹²,Patterson Nick²,O’Dushlaine Colm²,Schaffner Stephen F.²⁶,Gupta Sameer⁷,Chowdhury Fahima⁵,Sheikh Alaullah⁵,Shin Ok Sarah³,Ellis Crystal³,Becker Christine E.⁸,Stuart Lynda M.²⁸,Calderwood Stephen B.³⁹¹⁰,Ryan Edward T.³⁶⁹,Qadri Firdausi⁵,Sabeti Pardis C.¹²⁶,LaRocque Regina C.³⁹

Affiliation:

1. Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.

2. Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

3. Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA.

4. Department of Pediatrics, Harvard Medical School, Boston, MA 02114, USA.

5. International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.

6. Department of Immunology and Infectious Disease, Harvard School of Public Health, Boston, MA 02115, USA.

7. Harvard Medical School, Boston, MA 02115, USA.

8. Developmental Immunology and Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

9. Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.

10. Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.

Abstract

Natural selection in a Bangladeshi population from the cholera-endemic Ganges River Delta has targeted genes associated with cholera resistance and an innate immunity pathway activated by Vibrio cholerae .

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference88 articles.

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2. Report of the 1966-67 cholera vaccine field trial in rural East Pakistan. 2. Results of the serological surveys in the study population—The relationship of case rate to antibody titre and an estimate of the inapparent infection rate with Vibrio cholerae.;Mosley W. H.;Bull. World Health Organ.,1969

3. Seroepidemiological Studies of EI Tor Cholera in Bangladesh: Association of Serum Antibody Levels with Protection

4. Cholera's western front

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