Urine TMPRSS2:ERG Fusion Transcript Stratifies Prostate Cancer Risk in Men with Elevated Serum PSA-Reference-Cited by-同舟云学术

Urine TMPRSS2:ERG Fusion Transcript Stratifies Prostate Cancer Risk in Men with Elevated Serum PSA

Published:2011-08-03 Issue:94 Volume:3 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Tomlins Scott A.¹,Aubin Sheila M. J.²,Siddiqui Javed¹,Lonigro Robert J.¹³,Sefton-Miller Laurie¹,Miick Siobhan²,Williamsen Sarah²,Hodge Petrea²,Meinke Jessica²,Blase Amy²,Penabella Yvonne²,Day John R.²,Varambally Radhika¹,Han Bo¹,Wood David⁴,Wang Lei¹,Sanda Martin G.⁵,Rubin Mark A.⁶,Rhodes Daniel R.¹,Hollenbeck Brent⁴,Sakamoto Kyoko⁷,Silberstein Jonathan L.⁷,Fradet Yves⁸,Amberson James B.⁹,Meyers Stephanie⁴,Palanisamy Nallasivam¹,Rittenhouse Harry²,Wei John T.⁴,Groskopf Jack²,Chinnaiyan Arul M.¹³⁴¹⁰

Affiliation:

1. Michigan Center for Translational Pathology, Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

2. Gen-Probe Inc., San Diego, CA 92121, USA.

3. Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

4. Department of Urology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

5. Division of Urology, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

6. Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10021, USA.

7. Department of Urology, University of California at San Diego Medical Center and San Diego Veterans Affairs, San Diego, CA 92161, USA.

8. Department of Urology, University of Laval, Quebec, Quebec G1V 0A6, Canada.

9. Dianon Systems Inc., Shelton, CT 06484, USA.

10. Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

Abstract

Urine TMPRSS2:ERG gene fusion could be used for stratification of patients at higher risk for prostate cancer.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference42 articles.

1. Use of the Prostate-Specific Antigen Test among U.S. Men: Findings from the 2005 National Health Interview Survey

2. Prostate cancer screening in the Prostate, Lung, Colorectal and Ovarian cancer screening trial: update on findings from the initial four rounds of screening in a randomized trial

3. Screening and Prostate-Cancer Mortality in a Randomized European Study

4. Pathologic Characteristics of Cancers Detected in the Prostate Cancer Prevention Trial: Implications for Prostate Cancer Detection and Chemoprevention

5. Prevalence of Prostate Cancer among Men with a Prostate-Specific Antigen Level ≤4.0 ng per Milliliter

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