Manipulating the Bioenergetics of Alloreactive T Cells Causes Their Selective Apoptosis and Arrests Graft-Versus-Host Disease-Reference-Cited by-同舟云学术

Manipulating the Bioenergetics of Alloreactive T Cells Causes Their Selective Apoptosis and Arrests Graft-Versus-Host Disease

Author:

Gatza Erin¹,Wahl Daniel R.²,Opipari Anthony W.³,Sundberg Thomas B.⁴,Reddy Pavan⁵,Liu Chen⁶,Glick Gary D.²⁴,Ferrara James L. M.¹

Affiliation:

1. Department of Pediatrics, University of Michigan, Ann Arbor, MI 48109, USA.

2. Chemical Biology Doctoral Program, University of Michigan, Ann Arbor, MI 48109, USA.

3. Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI 48109, USA.

4. Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.

5. Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.

6. Department of Pathology, University of Florida College of Medicine, Gainesville, FL 32610, USA.

Abstract

Bioenergetic properties differentiate alloreactive T cells from other proliferating cells and can be exploited to arrest GVHD in mice.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference44 articles.

3. D. Voet J. G. Voet Biochemistry (J. Wiley & Sons New York ed. 3 2004) pp. xv 1591.

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