Chitinase 3–Like 1 Suppresses Injury and Promotes Fibroproliferative Responses in Mammalian Lung Fibrosis-Reference-Cited by-同舟云学术

Chitinase 3–Like 1 Suppresses Injury and Promotes Fibroproliferative Responses in Mammalian Lung Fibrosis

Published:2014-06-11 Issue:240 Volume:6 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Zhou Yang¹,Peng Hong²,Sun Huanxing¹,Peng Xueyan¹,Tang Chuyan¹,Gan Ye¹,Chen Xiaosong¹,Mathur Aditi¹,Hu Buqu¹,Slade Martin D.¹,Montgomery Ruth R.³,Shaw Albert C.³,Homer Robert J.⁴,White Eric S.⁵,Lee Chang-Min¹,Moore Meagan W.¹,Gulati Mridu¹,Geun Lee Chun¹,Elias Jack A.⁶,Herzog Erica L.¹

Affiliation:

1. Section of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Yale School of Medicine, New Haven, CT 06520, USA.

2. Department of Respiratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, PR China.

3. Program on Aging, Yale School of Medicine, New Haven, CT 06520, USA.

4. Department of Pathology, Yale School of Medicine, New Haven, CT 06520, USA.

5. Department of Medicine, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA.

6. Division of Biology and Medicine, Warren Alpert School of Medicine at Brown University, Providence, RI 02912, USA.

Abstract

Chitinase 3–like 1 protects against lung injury but has a profibrotic role during the repair phase.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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