Instructive Nanofiber Scaffolds with VEGF Create a Microenvironment for Arteriogenesis and Cardiac Repair

Author:

Lin Yi-Dong12,Luo Chwan-Yau3,Hu Yu-Ning3,Yeh Ming-Long2,Hsueh Ying-Chang45,Chang Min-Yao24,Tsai Da-Ching4,Wang Jieh-Neng6,Tang Ming-Jer57,Wei Erika I. H.1,Springer Matthew L.8,Hsieh Patrick C. H.12345

Affiliation:

1. Institute of Biomedical Sciences, Academia Sinica, Taipei 11574, Taiwan.

2. Institute of Biomedical Engineering, National Cheng Kung University, Tainan 70101, Taiwan.

3. Department of Surgery, National Cheng Kung University Hospital, Tainan 70403, Taiwan.

4. Institute of Clinical Medicine, National Cheng Kung University, Tainan 70101, Taiwan.

5. Institute of Basic Medicine, National Cheng Kung University, Tainan 70101, Taiwan.

6. Department of Pediatrics, National Cheng Kung University Hospital, Tainan 70403, Taiwan.

7. Institute of Physiology, National Cheng Kung University, Tainan 70101, Taiwan.

8. Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.

Abstract

An intramyocardial microenvironment was created using nanofibers and VEGF for endogenous cardiac repair after infarction.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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