The Role of Dimethylarginine Dimethylaminohydrolase in Idiopathic Pulmonary Fibrosis-Reference-Cited by-同舟云学术

The Role of Dimethylarginine Dimethylaminohydrolase in Idiopathic Pulmonary Fibrosis

Published:2011-06-15 Issue:87 Volume:03 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Pullamsetti Soni Savai¹²,Savai Rajkumar¹²,Dumitrascu Rio²,Dahal Bhola Kumar²,Wilhelm Jochen²,Konigshoff Melanie³,Zakrzewicz Dariusz²,Ghofrani Hossein Ardeschir²,Weissmann Norbert²,Eickelberg Oliver³,Guenther Andreas²⁴,Leiper James⁵,Seeger Werner¹²,Grimminger Friedrich²,Schermuly Ralph Theo¹²

Affiliation:

1. Max-Planck Institute for Heart and Lung Research, Bad Nauheim 61231, Germany.

2. University of Giessen Lung Centre, Giessen 35392, Germany.

3. Comprehensive Pneumology Center, University Hospital Grosshadern, Ludwig-Maximilians-University, and Helmholtz Zentrum München, Munich 81377, Germany.

4. Lungenfachklinik Waldhof-Elgershausen, Greifenstein 35753, Germany.

5. Medical Research Council, Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.

Abstract

Inhibition of dimethylarginine dimethylaminohydrolase enzyme in lung attenuates two hallmarks of pulmonary fibrosis, excess cells and excess collagen, thereby offering a therapeutic approach.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference56 articles.

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