Immunotherapy Against HPV16/18 Generates Potent T H 1 and Cytotoxic Cellular Immune Responses

Author:

Bagarazzi Mark L.1,Yan Jian1,Morrow Matthew P.1,Shen Xuefei1,Parker R. Lamar2,Lee Jessica C.1,Giffear Mary1,Pankhong Panyupa3,Khan Amir S.1,Broderick Kate E.1,Knott Christine1,Lin Feng1,Boyer Jean D.3,Draghia-Akli Ruxandra1,White C. Jo1,Kim J. Joseph1,Weiner David B.3,Sardesai Niranjan Y.1

Affiliation:

1. Inovio Pharmaceuticals Inc., 1787 Sentry Parkway West, Building 18, Suite 400, Blue Bell, PA 19422, USA.

2. Lyndhurst Clinical Research, Winston-Salem, NC 27103, USA.

3. Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Abstract

CD8 + T cells with cytolytic activity are induced after therapeutic human papillomavirus vaccination in humans.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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