Targeted Delivery of PLK1-siRNA by ScFv Suppresses Her2 + Breast Cancer Growth and Metastasis-Reference-Cited by-同舟云学术

Targeted Delivery of PLK1-siRNA by ScFv Suppresses Her2 + Breast Cancer Growth and Metastasis

Published:2012-04-18 Issue:130 Volume:4 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Yao Yan-dan¹,Sun Tian-meng²,Huang Song-yin¹,Dou Shuang²,Lin Ling¹,Chen Jia-ning¹,Ruan Jian-bin²,Mao Cheng-qiong²,Yu Feng-yan¹,Zeng Mu-sheng³,Zang Jian-ye²,Liu Qiang¹,Su Feng-xi¹,Zhang Peter⁴,Lieberman Judy⁵,Wang Jun²,Song Erwei¹

Affiliation:

1. Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.

2. Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei 230027, China.

3. State Key Laboratory of Oncology in Southern China, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.

4. Shanghai GenePharma Co. Ltd., Shanghai 201203, China.

5. Immune Disease Institute and Program in Cellular and Molecular Medicine, Children’s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.

Abstract

Antibody-mediated delivery of anticancer siRNAs suppresses Her2 + breast cancer growth and metastasis.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference35 articles.

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4. Polo-like kinases and the orchestration of cell division

5. Targeting Polo-like Kinase in Cancer Therapy: Fig. 1.

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