A Model for Personalized in Vivo Analysis of Human Immune Responsiveness-Reference-Cited by-同舟云学术

A Model for Personalized in Vivo Analysis of Human Immune Responsiveness

Published:2012-03-14 Issue:125 Volume:4 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Kalscheuer Hannes¹²,Danzl Nichole²,Onoe Takashi¹,Faust Ted¹,Winchester Robert³⁴,Goland Robin³⁵,Greenberg Ellen³⁵,Spitzer Thomas R.⁶,Savage David G.⁷,Tahara Hiroyuki²,Choi Goda²,Yang Yong-Guang¹²,Sykes Megan¹²⁸

Affiliation:

1. Transplantation Biology Research Center, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.

2. Columbia Center for Translational Immunology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

3. Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

4. Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

5. Naomi Berrie Diabetes Center, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

6. Division of Bone Marrow Transplantation, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

7. Division of Hematology/Oncology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

8. Departments of Surgery and Microbiology/Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

Abstract

Personalized humanized mice can model intrinsic defects in human immune disease.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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5. Antigen-specific human T-cell responses and T cell–dependent production of human antibodies in a humanized mouse model.;Tonomura N.;Blood,2008

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