Antisense Gets a Grip on miR-122 in Chimpanzees

Author:

Branch Andrea D.1,Rice Charles M.2

Affiliation:

1. Division of Liver Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.

2. Center for the Study of Hepatitis C, Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.

Abstract

Hepatitis C virus–infected chimpanzees were treated with an antisense RNA that binds to and blocks the function of a microRNA that enhances viral replication without causing major side effects.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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