Antisense Gets a Grip on miR-122 in Chimpanzees-Reference-Cited by-同舟云学术

Antisense Gets a Grip on miR-122 in Chimpanzees

Published:2010-01-06 Issue:13 Volume:2 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Branch Andrea D.¹,Rice Charles M.²

Affiliation:

1. Division of Liver Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.

2. Center for the Study of Hepatitis C, Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.

Abstract

Hepatitis C virus–infected chimpanzees were treated with an antisense RNA that binds to and blocks the function of a microRNA that enhances viral replication without causing major side effects.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference20 articles.

1. Therapeutic silencing of microRNA-122 in primates with chronic HCV infection.;Lanford R. E.;Science

2. Optimal therapy in genotype 1 patients

3. Protease and polymerase inhibitors for the treatment of hepatitis C

4. The quasispecies nature and biological implications of the hepatitis C virus

5. Modulation of Hepatitis C Virus RNA Abundance by a Liver-Specific MicroRNA

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The role of miRNA in selected tumors development: Potential use in diagnostics;Postępy Higieny i Medycyny Doświadczalnej;2021-01-18

2. miR-122 Inhibits Hepatocarcinoma Cell Progression by Targeting LMNB2;Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics;2020-02-07

3. miR-122-mediated translational repression of PEG10 and its suppression in human hepatocellular carcinoma;Journal of Translational Medicine;2016-07-02

4. Complexity of microRNA function and the role of isomiRs in lipid homeostasis;Journal of Lipid Research;2013-05

5. Can tobacco use promote HCV-induced miR-122 hijacking and hepatocarcinogenesis?;Medical Hypotheses;2013-02