The hallmarks of successful anticancer immunotherapy

Author:

Galluzzi Lorenzo123ORCID,Chan Timothy A.456ORCID,Kroemer Guido378910ORCID,Wolchok Jedd D.611ORCID,López-Soto Alejandro12

Affiliation:

1. Department of Radiation Oncology, Weill Cornell Medical College, New York, NY 10065, USA.

2. Sandra and Edward Meyer Cancer Center, New York, NY 10065, USA.

3. Université Paris Descartes/Paris V, 75006 Paris, France.

4. Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

5. Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

6. Weill Cornell School of Medicine, New York, NY 10065, USA.

7. Equipe 11 labellisée Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, 75006 Paris, France.

8. INSERM, U1138, 75006 Paris, France.

9. Université Pierre et Marie Curie/Paris VI, 75006 Paris, France.

10. Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Center, 94805 Villejuif, France.

11. Department of Medicine, Parker Institute and Ludwig Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

12. Departamento de Biología Funcional, Área de Inmunología, Universidad de Oviedo, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), 33006 Oviedo, Spain.

Abstract

Various features of the tumor and immune system influence the success of immunotherapy.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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