Rapid pathogen-specific phenotypic antibiotic susceptibility testing using digital LAMP quantification in clinical samples-Reference-Cited by-同舟云学术

Rapid pathogen-specific phenotypic antibiotic susceptibility testing using digital LAMP quantification in clinical samples

Published:2017-10-04 Issue:410 Volume:9 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Schoepp Nathan G.¹^ORCID,Schlappi Travis S.¹^ORCID,Curtis Matthew S.¹^ORCID,Butkovich Slava S.¹^ORCID,Miller Shelley²^ORCID,Humphries Romney M.²,Ismagilov Rustem F.¹^ORCID

Affiliation:

1. Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA.

2. Department of Pathology and Laboratory Medicine, University of California, Los Angeles, 10888 Le Conte Avenue, Brentwood Annex, Los Angeles, CA 90095, USA.

Abstract

Digital ultrafast loop-mediated isothermal amplification determines phenotypic antibiotic susceptibility of Escherichia coli in clinical urine samples in less than 30 min.

Funder

National Institutes of Health

Burroughs Wellcome Fund

Defense Sciences Office, DARPA

Joseph J. Jacobs Institute for Molecular Engineering for Medicine

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference101 articles.

1. Antibiotic resistance—the need for global solutions

2. J. O’Neill Tackling drug-resistant infections globally: Final report and recommendations (2016); https://amr-review.org/Publications.html.