Using fMRI connectivity to define a treatment-resistant form of post-traumatic stress disorder-Reference-Cited by-同舟云学术

Using fMRI connectivity to define a treatment-resistant form of post-traumatic stress disorder

Published:2019-04-03 Issue:486 Volume:11 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Etkin Amit¹²³⁴^ORCID,Maron-Katz Adi¹²³⁴^ORCID,Wu Wei¹²³⁴⁵^ORCID,Fonzo Gregory A.¹²³⁴,Huemer Julia¹²³^ORCID,Vértes Petra E.⁶⁷⁸^ORCID,Patenaude Brian¹²³⁴,Richiardi Jonas⁹¹⁰^ORCID,Goodkind Madeleine S.¹¹¹²,Keller Corey J.¹²³⁴^ORCID,Ramos-Cejudo Jaime⁴¹³^ORCID,Zaiko Yevgeniya V.¹²³^ORCID,Peng Kathy K.¹³,Shpigel Emmanuel¹²³⁴,Longwell Parker¹²³⁴^ORCID,Toll Russ T.¹²³⁴^ORCID,Thompson Allison¹^ORCID,Zack Sanno¹,Gonzalez Bryan⁴¹³,Edelstein Raleigh¹²³⁴^ORCID,Chen Jingyun⁴¹³,Akingbade Irene¹³⁴^ORCID,Weiss Elizabeth¹³,Hart Roland⁴¹³,Mann Silas⁴¹³^ORCID,Durkin Kathleen⁴¹³,Baete Steven H.⁴¹¹¹²^ORCID,Boada Fernando E.⁴¹⁴¹⁵^ORCID,Genfi Afia⁴¹³,Autea Jillian¹²³⁴,Newman Jennifer⁴¹³^ORCID,Oathes Desmond J.¹⁶^ORCID,Lindley Steven E.¹³^ORCID,Abu-Amara Duna⁴¹³^ORCID,Arnow Bruce A.¹^ORCID,Crossley Nicolas¹⁷¹⁸^ORCID,Hallmayer Joachim¹²³^ORCID,Fossati Silvia⁴¹³^ORCID,Rothbaum Barbara O.¹⁹,Marmar Charles R.⁴¹³,Bullmore Edward T.⁶²⁰²¹^ORCID,O’Hara Ruth¹³^ORCID

Affiliation:

1. Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94304, USA.

2. Wu Tsai Neurosciences Institute at Stanford, Stanford University, Stanford, CA 94304, USA.

3. Sierra Pacific Mental Illness Research, Education, and Clinical Center (MIRECC), Veterans Affairs Palo Alto Healthcare System, Palo Alto, CA 94394, USA.

4. Steven and Alexandra Cohen Veterans Center for Post-traumatic Stress and Traumatic Brain Injury, New York University Langone School of Medicine, New York, NY 10016, USA.

5. School of Automation Science and Engineering, South China University of Technology, Guangzhou, Guangdong 510640, China.

6. Department of Psychiatry, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB2 0SZ, UK.

7. School of Mathematical Sciences, Queen Mary University of London, London E1 4NS, UK.

8. The Alan Turing Institute, London NW1 2DB, UK.

9. Department of Medical Radiology, Lausanne University Hospital, Lausanne, Switzerland.

10. Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland.

11. New Mexico Veterans Affairs Healthcare System, Albuquerque, NM 87108, USA.

12. Department of Psychiatry and Behavioral Sciences, University of New Mexico, Albuquerque, NM 87131, USA.

13. Department of Psychiatry, New York University Langone School of Medicine, New York, NY 10016, USA.

14. Center for Advanced Imaging Innovation and Research (CAI2R), NYU School of Medicine, New York, NY 10016, USA.

15. Center for Biomedical Imaging, Department of Radiology, NYU School of Medicine, New York, NY 10016, USA.

16. Center for Neuromodulation in Depression and Stress, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

17. Department of Psychiatry, School of Medicine, Pontificia Universidad Católica de Chile, 6513677 Santiago, Chile.

18. Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, UK.

19. Trauma and Anxiety Recovery Program, Department of Psychiatry, Emory University School of Medicine, Atlanta, GA 30322, USA.

20. Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge CB21 5EF, UK.

21. ImmunoPsychiatry, Alternative Discovery and Development, GlaxoSmithKline, Stevenage SG1 2NY, UK.

Abstract

A subgroup of patients with post-traumatic stress disorder, characterized by a particular brain and behavioral signature, showed a poor treatment outcome.

Funder

National Institutes of Health

Medical Research Council

National Science Foundation

National Key Research and Development Plan of China

Steven A. and Alexandra M. Cohen Foundation

funds from Ann and Peter Tarlton

Sierra-Pacific Mental Illness Research, Education and Clinical Center (MIRECC) at the Palo Alto VA

Cohen Veterans Bioscience

Office of Academic Affiliations, Advanced Fellowship Program in Mental Illness Research and Treatment, Department of Veterans Affairs

Publisher

American Association for the Advancement of Science (AAAS)