Fingolimod treatment abrogates chikungunya virus–induced arthralgia-Reference-Cited by-同舟云学术

Fingolimod treatment abrogates chikungunya virus–induced arthralgia

Published:2017-02 Issue:375 Volume:9 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Teo Teck-Hui¹,Chan Yi-Hao¹²,Lee Wendy W. L.¹²,Lum Fok-Moon¹,Amrun Siti Naqiah¹,Her Zhisheng¹,Rajarethinam Ravisankar³,Merits Andres⁴,Rötzschke Olaf¹,Rénia Laurent¹,Ng Lisa F. P.¹⁵⁶

Affiliation:

1. Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Singapore.

2. NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore.

3. Advanced Molecular Pathology Laboratory, A*STAR, Singapore, Singapore.

4. Institute of Technology, University of Tartu, 50411 Tartu, Estonia.

5. Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

6. Institute of Infection and Global Health, University of Liverpool, Liverpool, U.K.

Abstract

Abrogation of pathogenic CD4 + T cells to the joints with fingolimod (FTY720) treatment prevents chikungunya virus–induced joint pathology.

Funder

Agency for Science, Technology and Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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