Muse cell spheroids have therapeutic effect on corneal scarring wound in mice and tree shrews

Author:

Guo Yonglong123ORCID,Xue Yunxia3,Wang Peiyuan1ORCID,Cui Zekai4ORCID,Cao Jixing1,Liu Shiwei1,Yu Quan5,Zeng Qiaolang1,Zhu Deliang6,Xie Mengyuan6,Zhang Jun6,Li Zhijie123ORCID,Liu Hongwei7,Zhong Jingxiang1,Chen Jiansu1234ORCID

Affiliation:

1. Ophthalmology Department, First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China.

2. Key Laboratory for Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China.

3. Institute of Ophthalmology, Medical College, Jinan University, Guangzhou, China.

4. Aier Eye Institute, 18th floor, the New century building, #198 Furong Middle Road, Changsha, Hunan 410015, China.

5. Centric Laboratory, Medical College, Jinan University, Guangzhou, China.

6. Key Laboratory of Optoelectronic Information and Sensing Technologies, Guangdong Higher Educational Institutes, Jinan University, Guangzhou 510632, China.

7. Department of Plastic Surgery, First Affiliated Hospital of Jinan University, Guangzhou, China.

Abstract

Corneal stromal cells differentiated from Muse spheroids had therapeutic effects on wounded corneas in mice and tree shrews.

Funder

National Outstanding Youth Science Fund Project of National Natural Science Foundation of China

Project funded by China Postdoctoral Science Foundation

the Special Funds for Major Science and Technology Projects of Guangdong Province

Joint Fund of Basic and Applied Basic Research Fund of Guangdong Province

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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