Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening-Reference-Cited by-同舟云学术

Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening

Published:2019-11-20 Issue:519 Volume:11 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Lin Grant L.¹^ORCID,Wilson Kelli M.²^ORCID,Ceribelli Michele²,Stanton Benjamin Z.³^ORCID,Woo Pamelyn J.¹,Kreimer Sara¹^ORCID,Qin Elizabeth Y.¹,Zhang Xiaohu²,Lennon James¹,Nagaraja Surya¹,Morris Patrick J.²^ORCID,Quezada Michael¹,Gillespie Shawn M.¹^ORCID,Duveau Damien Y.²^ORCID,Michalowski Aleksandra M.⁴^ORCID,Shinn Paul²,Guha Rajarshi²^ORCID,Ferrer Marc²,Klumpp-Thomas Carleen²,Michael Sam²^ORCID,McKnight Crystal²^ORCID,Minhas Paras¹,Itkin Zina²^ORCID,Raabe Eric H.⁵^ORCID,Chen Lu²,Ghanem Reem¹,Geraghty Anna C.¹^ORCID,Ni Lijun¹,Andreasson Katrin I.¹^ORCID,Vitanza Nicholas A.¹^ORCID,Warren Katherine E.⁶,Thomas Craig J.²⁷^ORCID,Monje Michelle¹⁸⁹¹⁰¹¹^ORCID

Affiliation:

1. Department of Neurology, Stanford University School of Medicine, Stanford, CA 94305, USA.

2. Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA.

3. Center for Childhood Cancer and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children’s Hospital, The Ohio State University College of Medicine, Columbus, OH 43205, USA.

4. Laboratory of Cancer Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

5. Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

6. Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

7. Lymphoid Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

8. Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.

9. Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA.

10. Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.

11. Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

Abstract

High-throughput screens in DMG identify promising treatments, such as the combination of panobinostat and marizomib acting through metabolic collapse.

Funder

National Institutes of Health

Alex’s Lemonade Stand Foundation for Childhood Cancer

Virginia and D.K. Ludwig Fund for Cancer Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference43 articles.

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