Targeting redox heterogeneity to counteract drug tolerance in replicating Mycobacterium tuberculosis-Reference-Cited by-同舟云学术

Targeting redox heterogeneity to counteract drug tolerance in replicating Mycobacterium tuberculosis

Published:2019-11-13 Issue:518 Volume:11 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Mishra Richa¹²^ORCID,Kohli Sakshi¹²^ORCID,Malhotra Nitish³^ORCID,Bandyopadhyay Parijat¹²^ORCID,Mehta Mansi¹²,Munshi MohamedHusen¹²^ORCID,Adiga Vasista²^ORCID,Ahuja Vijay Kamal⁴,Shandil Radha K.⁴^ORCID,Rajmani Raju S.²,Seshasayee Aswin Sai Narain³,Singh Amit¹^ORCID

Affiliation:

1. Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.

2. Centre for Infectious Disease Research, Indian Institute of Science, Bangalore 560012, India.

3. National Centre for Biological Sciences (NCBS), Tata Institute of Fundamental Research (TIFR), Bangalore 560065, India.

4. Foundation for Neglected Disease Research, Bangalore 560065, India.

Abstract

Chloroquine resets the redox physiology of Mycobacterium tuberculosis to potentiate the efficacy of antibiotics in vivo.

Funder

Department of Biotechnology , Ministry of Science and Technology

DBT India Alliance

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference112 articles.

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