Sampling interstitial fluid from human skin using a microneedle patch

Author:

Samant Pradnya P.1ORCID,Niedzwiecki Megan M.23ORCID,Raviele Nicholas1,Tran Vilinh4,Mena-Lapaix Juan1,Walker Douglas I.234,Felner Eric I.5ORCID,Jones Dean P.4ORCID,Miller Gary W.26ORCID,Prausnitz Mark R.1ORCID

Affiliation:

1. School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.

2. Department of Environmental Health, Emory University, Atlanta, GA 30322, USA.

3. Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

4. Clinical Biomarkers Laboratory, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Emory University, Atlanta, GA 30322, USA.

5. Department of Pediatrics, Division of Endocrinology, Emory University School of Medicine, Atlanta, GA 30322, USA.

6. Department of Environmental Health Science, Columbia University, New York, NY 10032, USA.

Abstract

Interstitial fluid from skin sampled with a microneedle-based method identified clinically relevant metabolic biomarkers in humans compared to plasma.

Funder

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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