Therapeutic targeting of casein kinase 1δ in breast cancer-Reference-Cited by-同舟云学术

Therapeutic targeting of casein kinase 1δ in breast cancer

Published:2015-12-16 Issue:318 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Rosenberg Laura H.¹²,Lafitte Marie¹,Quereda Victor¹,Grant Wayne¹,Chen Weimin¹,Bibian Mathieu³,Noguchi Yoshihiko³,Fallahi Mohammad⁴,Yang Chunying⁵⁶,Chang Jenny C.⁷,Roush William R.³,Cleveland John L.⁵⁶,Duckett Derek R.¹

Affiliation:

1. Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, FL 33458, USA.

2. Cancer Research Technology Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge, CB22 3AT, UK.

3. Department of Chemistry, The Scripps Research Institute, Jupiter, FL 33458, USA.

4. Informatics Core, The Scripps Research Institute, Jupiter, FL 33458, USA.

5. Department of Cancer Biology, The Scripps Research Institute, Jupiter, FL 33458, USA.

6. Department of Tumor Biology, Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.

7. Methodist Cancer Center, Houston Methodist Hospital, 6445 Main Street, P21-34, Houston, TX 77030, USA.

Abstract

Casein kinase 1δ promotes breast tumorigenesis by activation of β-catenin and can be targeted in some breast cancers.

Funder

NIH

H. Lee Moffitt Cancer Center and Research Institute

NIH Molecular Library Screening Center Network

National Cancer Institute Comprehensive Cancer Center Support

Rendina Family Foundation

Shear Family Foundation

Think Pink Kids Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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