Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer-Reference-Cited by-同舟云学术

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Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer

Published:2015-11-11 Issue:313 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Schiavon Gaia¹²,Hrebien Sarah¹,Garcia-Murillas Isaac¹,Cutts Rosalind J.¹,Pearson Alex¹,Tarazona Noelia¹,Fenwick Kerry¹,Kozarewa Iwanka¹,Lopez-Knowles Elena¹,Ribas Ricardo¹,Nerurkar Ashutosh²,Osin Peter²,Chandarlapaty Sarat³,Martin Lesley-Ann¹,Dowsett Mitch¹²,Smith Ian E.¹²,Turner Nicholas C.¹²

Affiliation:

1. The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK.

2. Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK.

3. Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

Abstract

ESR1 mutations evolve during the treatment of metastatic breast cancer.

Funder

Susan G. Komen Foundation

National Health Service

NIHR Biomedical Research Centre at The Royal Marsden

Institute of Cancer Research, Cancer Research UK

Mary-Jean Mitchell Green Foundation

Cridlan Trust

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference21 articles.

1. Genetic heterogeneity and cancer drug resistance

2. Preexistence and Clonal Selection of MET Amplification in EGFR Mutant NSCLC

3. The patterns and dynamics of genomic instability in metastatic pancreatic cancer

4. HER2 discordance between primary breast cancer and its paired metastasis: tumor biology or test artefact? Insights through meta-analysis

5. Genome remodelling in a basal-like breast cancer metastasis and xenograft

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