CT-guided injection of a TRPV1 agonist around dorsal root ganglia decreases pain transmission in swine-Reference-Cited by-同舟云学术

CT-guided injection of a TRPV1 agonist around dorsal root ganglia decreases pain transmission in swine

Published:2015-09-16 Issue:305 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Brown Jacob D.¹,Saeed Maythem¹,Do Loi¹,Braz Joao²,Basbaum Allan I.²,Iadarola Michael J.³,Wilson David M.¹,Dillon William P.¹

Affiliation:

1. Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94117, USA.

2. Department of Anatomy, University of California, San Francisco, San Francisco, CA 94117, USA.

3. Department of Perioperative Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.

Abstract

Delivery of resiniferatoxin under CT guidance around lumbar dorsal root ganglia in pigs resulted in selective deletion of nociceptive neurons and lasting analgesia.

Funder

NIH

Radiological Society of North America

Research and Education Foundation

NIH T32 Postdoctoral Training

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference41 articles.

1. The Search for a Better Analgesic

2. A Capsule History of Pain Management

3. Opioids and Chronic Neuropathic Pain

4. Nonsurgical Interventional Therapies for Low Back Pain

5. Molecular Signatures of Mouse TRPV1-Lineage Neurons Revealed by RNA-Seq Transcriptome Analysis

Cited by 45 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Resiniferatoxin for permanent pain relief in cancer patients;TRP Channels as Therapeutic Targets;2024

2. Resiniferatoxin: Nature’s Precision Medicine to Silence TRPV1-Positive Afferents;International Journal of Molecular Sciences;2023-10-10

3. Thoracic Dorsal Root Ganglion Application of Resiniferatoxin Reduces Myocardial Ischemia-Induced Ventricular Arrhythmias;Biomedicines;2023-10-07

4. Analgesia after dorsal root ganglionic injection under CT-guidance in a patient with intractable phantom limb pain;Pain Medicine;2023-03-28

5. TRPV1 Receptor Identification in Rainbow Trout (Oncorhynchus mykiss) and Evaluation of the Effects Produced by Ocimum basilicum Super Critical Fluid Extract;Fishes;2023-01-04