Targeting LGR5 + cells with an antibody-drug conjugate for the treatment of colon cancer
Author:
Affiliation:
1. Research and Early Development, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Abstract
Funder
Genentech Inc.
Publisher
American Association for the Advancement of Science (AAAS)
Subject
General Medicine
Reference32 articles.
1. Cancer stem cells: an evolving concept
2. Fourth World Antibody-Drug Conjugate Summit
3. Maturing antibody–drug conjugate pipeline hits 30
4. Identification of stem cells in small intestine and colon by marker gene Lgr5
5. Lineage Tracing Reveals Lgr5 + Stem Cell Activity in Mouse Intestinal Adenomas
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