Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory-Reference-Cited by-同舟云学术

Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory

Published:2015-12-09 Issue:317 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Oliveira Giacomo¹²,Ruggiero Eliana¹³,Stanghellini Maria Teresa Lupo⁴,Cieri Nicoletta¹,D’Agostino Mattia¹²,Fronza Raffaele³,Lulay Christina³,Dionisio Francesca⁵,Mastaglio Sara¹⁴,Greco Raffaella⁴,Peccatori Jacopo⁴,Aiuti Alessandro⁵,Ambrosi Alessandro²,Biasco Luca⁵,Bondanza Attilio⁴⁶,Lambiase Antonio⁷,Traversari Catia⁷,Vago Luca⁴⁸,von Kalle Christof³,Schmidt Manfred³,Bordignon Claudio²⁷,Ciceri Fabio²⁴⁸,Bonini Chiara¹²

Affiliation:

1. Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, Program in Immunology and Bio-Immunotherapy of Cancer (PIBIC), San Raffaele Scientific Institute, Milan 20132, Italy.

2. Vita-Salute San Raffaele University, Milan 20132, Italy.

3. Department of Translational Oncology, National Center for Tumor Diseases and German Cancer Research Center, Heidelberg 69120, Germany.

4. Hematology and Bone Marrow Transplantation Unit, San Raffaele Scientific Institute, Milan 20132, Italy.

5. Telethon Institute for Gene Therapy (HSR-TIGET), San Raffaele Scientific Institute, Milan 20132, Italy.

6. Innovative Immunotherapies Unit, Division of Immunology, Transplantation and Infectious Diseases, PIBIC, San Raffaele Scientific Institute, Milan 20132, Italy.

7. MolMed S.p.A, Milan 20132, Italy.

8. Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, Milan 20132, Italy.

Abstract

Antigen exposure and differentiation phenotype influence long-term persistence of memory T cells after hematopoietic stem cell transplant.

Funder

Fondazione Cariplo

Italian Ministry of Research and University

Italian Association for Cancer Research

Eranet Transcan Haplo-Immune

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference37 articles.