A glucagon-like peptide-1 receptor agonist reduces intracranial pressure in a rat model of hydrocephalus-Reference-Cited by-同舟云学术

A glucagon-like peptide-1 receptor agonist reduces intracranial pressure in a rat model of hydrocephalus

Published:2017-08-23 Issue:404 Volume:9 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Botfield Hannah F.¹²^ORCID,Uldall Maria S.³^ORCID,Westgate Connar S. J.¹²^ORCID,Mitchell James L.¹²⁴^ORCID,Hagen Snorre M.³^ORCID,Gonzalez Ana Maria⁵^ORCID,Hodson David J.¹²⁶^ORCID,Jensen Rigmor H.³,Sinclair Alexandra J.¹²⁴^ORCID

Affiliation:

1. Institute of Metabolism and Systems Research, University of Birmingham, Edgbaston B15 2TT, UK.

2. Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham B15 2TH, UK.

3. Danish Headache Center, Clinic of Neurology, Rigshospitalet-Glostrup, University of Copenhagen, Nordre Ringvej 69, 2600 Glostrup, Denmark.

4. Department of Neurology, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.

5. Institute of Inflammation and Ageing, University of Birmingham, Edgbaston B15 2TT, UK.

6. Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK.

Abstract

GLP-1R agonists show promise as a therapeutic agent to lower intracranial pressure in rodents.

Funder

Wellcome Trust

Medical Research Council

National Institute for Health Research

University Of Birmingham

West Midlands Neuroscience Teaching and Research Fund

NIHR

Diabetes UK

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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5. Mechanisms of CSF secretion by the choroid plexus

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