An off-target effect of BX795 blocks herpes simplex virus type 1 infection of the eye-Reference-Cited by-同舟云学术

An off-target effect of BX795 blocks herpes simplex virus type 1 infection of the eye

Published:2018-02-14 Issue:428 Volume:10 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Jaishankar Dinesh¹²^ORCID,Yakoub Abraam M.³⁴,Yadavalli Tejabhiram¹^ORCID,Agelidis Alex¹⁴,Thakkar Neel¹^ORCID,Hadigal Satvik¹,Ames Joshua¹⁴^ORCID,Shukla Deepak¹²⁴^ORCID

Affiliation:

1. Department of Ophthalmology and Visual Sciences, University of Illinois Medical Center, Chicago, IL 60612, USA.

2. Department of Bioengineering, University of Illinois, Chicago, IL 60607, USA.

3. Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94304, USA.

4. Department of Microbiology and Immunology, University of Illinois, Chicago, IL 60612, USA.

Abstract

A kinase inhibitor shows promise as a topical antiviral against ocular herpes.

Funder

National Eye Institute

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference68 articles.

1. B. Roizman D. M. Knipe R. J. Whitley Herpes simplex viruses in Fields Virology (Lippincott Williams & Wilkins ed. 5 2007) pp. 2503–2602.

2. Genital Herpes: Insights into Sexually Transmitted Infectious Disease

3. Herpes simplex virus infections

4. Herpes Simplex Epithelial and Stromal Keratitis: An Epidemiologic Update

5. Ocular drug delivery systems: An overview

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