Medication development in opioid addiction: Meaningful clinical end points-Reference-Cited by-同舟云学术

Medication development in opioid addiction: Meaningful clinical end points

Published:2018-03-28 Issue:434 Volume:10 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Volkow Nora D.¹^ORCID,Woodcock Janet²^ORCID,Compton Wilson M.¹,Throckmorton Douglas C.²,Skolnick Phil¹,Hertz Sharon²^ORCID,Wargo Eric M.¹

Affiliation:

1. National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20892, USA.

2. Food and Drug Administration, Silver Spring, MD 20892, USA.

Abstract

The FDA’s “abstinence” outcome measure for approval of new medications to treat opioid-use disorders has been difficult to achieve; developing and validating alternative meaningful outcomes could facilitate drug development.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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5. Percentage of Subjects With No Heavy Drinking Days: Evaluation as an Efficacy Endpoint for AlcoholClinical Trials

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