Cognitive impairments induced by necrotizing enterocolitis can be prevented by inhibiting microglial activation in mouse brain

Author:

Niño Diego F.12ORCID,Zhou Qinjie12ORCID,Yamaguchi Yukihiro12,Martin Laura Y.12,Wang Sanxia12,Fulton William B.12ORCID,Jia Hongpeng12ORCID,Lu Peng12,Prindle Thomas12,Zhang Fan3ORCID,Crawford Joshua4,Hou Zhipeng5ORCID,Mori Susumu5,Chen Liam L.6,Guajardo Andrew6,Fatemi Ali7,Pletnikov Mikhail48ORCID,Kannan Rangaramanujam M.9ORCID,Kannan Sujatha10,Sodhi Chhinder P.12,Hackam David J.12ORCID

Affiliation:

1. Division of General Pediatric Surgery, Johns Hopkins University and Bloomberg Children’s Center, Johns Hopkins Hospital, Baltimore, MD 21287, USA.

2. Division of General Pediatric Surgery, Johns Hopkins University and Johns Hopkins Children’s Center, Johns Hopkins Hospital, Baltimore, MD 21287, USA.

3. Program of Immunology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

4. Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.

5. Department of Biomedical Engineering and The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.

6. Division of Neuropathology, Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.

7. Departments of Neurology and Pediatrics, Kennedy Krieger Institute and Johns Hopkins University School of Medicine, MD 21205, USA.

8. Department of Molecular and Comparative Pathobiology and Solomon H. Snyder Department of Neuroscience, Johns Hopkins University and Johns Hopkins Children’s Center, Johns Hopkins Hospital, Baltimore, MD 21205, USA.

9. Center for Nanomedicine, Wilmer Eye Institute, Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

10. Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Abstract

Necrotizing enterocolitis–induced brain injury in mice can be prevented with an oral nanotherapeutic that targets microglia.

Funder

National Institutes of Health

National Institute of Neurological Disorders and Stroke

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Cited by 93 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3