Targeted antibody and cytokine cancer immunotherapies through collagen affinity-Reference-Cited by-同舟云学术

Targeted antibody and cytokine cancer immunotherapies through collagen affinity

Published:2019-04-10 Issue:487 Volume:11 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Ishihara Jun¹^ORCID,Ishihara Ako¹^ORCID,Sasaki Koichi¹^ORCID,Lee Steve Seung-Young²^ORCID,Williford John-Michael¹^ORCID,Yasui Mariko³,Abe Hiroyuki³,Potin Lambert¹⁴^ORCID,Hosseinchi Peyman¹^ORCID,Fukunaga Kazuto¹^ORCID,Raczy Michal M.¹^ORCID,Gray Laura T.¹^ORCID,Mansurov Aslan¹^ORCID,Katsumata Kiyomitsu¹^ORCID,Fukayama Masashi³^ORCID,Kron Stephen J.²^ORCID,Swartz Melody A.¹⁵^ORCID,Hubbell Jeffrey A.¹^ORCID

Affiliation:

1. Institute for Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.

2. Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA.

3. Department of Pathology, University of Tokyo, 113-8655 Tokyo, Japan.

4. Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.

5. Ben May Department for Cancer Research, University of Chicago, Chicago, IL 60637, USA.

Abstract

An engineered cancer immunotherapy using a collagen-binding domain enhances efficacy and reduces adverse events.

Funder

National Cancer Institute

National Institute of Biomedical Imaging and Bioengineering

European Research Commission grant

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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