Remdesivir (GS-5734) protects African green monkeys from Nipah virus challenge-Reference-Cited by-同舟云学术

Remdesivir (GS-5734) protects African green monkeys from Nipah virus challenge

Published:2019-05-29 Issue:494 Volume:11 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Lo Michael K.¹^ORCID,Feldmann Friederike²^ORCID,Gary Joy M.¹,Jordan Robert³,Bannister Roy³^ORCID,Cronin Jacqueline⁴^ORCID,Patel Nishi R.¹,Klena John D.¹,Nichol Stuart T.¹,Cihlar Tomas³,Zaki Sherif R.¹^ORCID,Feldmann Heinz⁴^ORCID,Spiropoulou Christina F.¹^ORCID,de Wit Emmie⁴^ORCID

Affiliation:

1. Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.

2. Rocky Mountain Veterinary Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA.

3. Gilead Sciences, Foster City, CA 94404, USA.

4. Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA.

Abstract

Treatment of African green monkeys with remdesivir (GS-5734) 24 hours after lethal Nipah virus challenge resulted in 100% survival.

Funder

Centers for Disease Control and Prevention

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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