Retinol binding protein 3 is increased in the retina of patients with diabetes resistant to diabetic retinopathy

Author:

Yokomizo Hisashi1ORCID,Maeda Yasutaka1ORCID,Park Kyoungmin1,Clermont Allen C.12,Hernandez Sonia L.1ORCID,Fickweiler Ward12ORCID,Li Qian1,Wang Chih-Hao1,Paniagua Samantha M.1,Simao Fabricio1,Ishikado Atsushi1,Sun Bei1ORCID,Wu I-Hsien1ORCID,Katagiri Sayaka1ORCID,Pober David M.1,Tinsley Liane J.1ORCID,Avery Robert L.3,Feener Edward P.14,Kern Timothy S.5ORCID,Keenan Hillary A.14ORCID,Aiello Lloyd Paul126ORCID,Sun Jennifer K.126ORCID,King George L.146ORCID

Affiliation:

1. Research Division, Joslin Diabetes Center, Boston, MA 02215, USA.

2. Beetham Eye Institute, Joslin Diabetes Center, Boston, MA 02215, USA.

3. California Retina Consultants, Santa Barbara, CA 93103, USA.

4. Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.

5. Center for Translational Vision Research, Gavin Herbert Eye Institute, Irvine, CA 92697, USA.

6. Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA.

Abstract

Retinol binding protein 3 may protect against the progression of diabetic retinopathy by inhibiting glucose uptake into retinal cells.

Funder

National Eye Institute

National Institute of Diabetes and Digestive and Kidney Diseases

Juvenile Diabetes Research Foundation

NIDDK Diabetes Research Center

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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