A gastric resident drug delivery system for prolonged gram-level dosing of tuberculosis treatment-Reference-Cited by-同舟云学术

A gastric resident drug delivery system for prolonged gram-level dosing of tuberculosis treatment

Published:2019-03-13 Issue:483 Volume:11 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Verma Malvika¹²³^ORCID,Vishwanath Karan²^ORCID,Eweje Feyisope²⁴⁵,Roxhed Niclas²⁶^ORCID,Grant Tyler²⁷,Castaneda Macy²,Steiger Christoph²⁵⁷^ORCID,Mazdiyasni Hormoz²⁷^ORCID,Bensel Taylor²⁷,Minahan Daniel²⁷^ORCID,Soares Vance²⁷^ORCID,Salama John A. F.²,Lopes Aaron²⁷,Hess Kaitlyn²⁷^ORCID,Cleveland Cody²⁷^ORCID,Fulop Daniel J.²^ORCID,Hayward Alison²⁷⁸^ORCID,Collins Joy²⁷^ORCID,Tamang Siddartha M.²⁷,Hua Tiffany²⁷,Ikeanyi Chinonyelum²⁴,Zeidman Gal²⁴^ORCID,Mule Elizabeth²⁷^ORCID,Boominathan Sooraj²⁹,Popova Ellena²¹⁰^ORCID,Miller Jonathan B.⁴¹¹^ORCID,Bellinger Andrew M.²⁷¹²,Collins David¹³¹⁴^ORCID,Leibowitz Dalia³⁴,Batra Shelly¹⁵,Ahuja Sandeep¹⁵,Bajiya Manju¹⁵,Batra Sonali¹⁵^ORCID,Sarin Rohit¹⁶,Agarwal Upasna¹⁶,Khaparde Sunil D.¹⁷,Gupta Neeraj K.¹⁸,Gupta Deepak¹⁹,Bhatnagar Anuj K.²⁰^ORCID,Chopra Kamal K.²¹,Sharma Nandini²²,Khanna Ashwani²³,Chowdhury Jayeeta²⁴,Stoner Robert³²⁵,Slocum Alexander H.³⁴,Cima Michael J.²³²⁶^ORCID,Furin Jennifer²⁷^ORCID,Langer Robert¹²³⁴⁷^ORCID,Traverso Giovanni²³⁴⁵⁷^ORCID

Affiliation:

1. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

2. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

3. Tata Center for Technology and Design, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

4. Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

5. Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.

6. Department of Micro and Nanosystems, KTH Royal Institute of Technology, Stockholm 10044, Sweden.

7. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

8. Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

9. Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

10. Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

11. Sloan School of Management, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

12. Cardiovascular Division, Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.

13. Management Sciences for Health, Medford, MA 02155, USA.

14. Boston University School of Public Health, Boston, MA 02118, USA.

15. Operation ASHA, New Delhi 110076, India.

16. National Institute of Tuberculosis and Respiratory Diseases, New Delhi 110030, India.

17. Former Deputy Director General and Head of Central TB Division, Government of India, New Delhi 110011, India.

18. Department of Respiratory Medicine, Safdarjung Hospital, New Delhi 110029, India.

19. Division of Pulmonary and Critical Care Medicine, All India Institute of Medical Sciences, New Delhi 110029, India.

20. Rajan Babu Institute for Pulmonary Medicine and Tuberculosis, New Delhi 110009, India.

21. New Delhi Tuberculosis Centre, New Delhi 110002, India.

22. Department of Community Medicine, Maulana Azad Medical College, New Delhi 110002, India.

23. Lok Nayak Hospital Chest Clinic, New Delhi 110002, India.

24. Tata Trusts, Mumbai 400001, India.

25. MIT Energy Initiative, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

26. Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

27. Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA 02115, USA.

Abstract

A retrievable device, compatible with nasogastric tube administration, releases grams of drug over weeks while residing in the stomach.

Funder

National Science Foundation

National Institutes of Health

Bill and Melinda Gates Foundation

Brigham and Women’s Hospital

MIT Tata Center

National Science Foundation Graduate Research Fellowship

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference68 articles.

1. E. Sabaté Adherence to Long-Term Therapies: Evidence for Action (World Health Organization 2003); http://apps.who.int/iris/bitstream/handle/10665/42682/9241545992.pdf.

2. Past, Present, and Future Drug Delivery Systems for Antiretrovirals

3. World Health Organization Treatment of Tuberculosis: Guidelines—4th Edition (2010); http://apps.who.int/iris/bitstream/handle/10665/44165/9789241547833_eng.pdf.

4. Emerging Frontiers in Drug Delivery

5. Polymers in controlled drug delivery systems;Shaik M. R.;Int. J. Pharma Sci.,2012

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