Treating murine inflammatory diseases with an anti-erythrocyte antibody

Author:

Crow Andrew R.123,Kapur Rick12345ORCID,Koernig Sandra6,Campbell Ian K.6,Jen Chao-Ching23ORCID,Mott Patrick J.23ORCID,Marjoram Danielle23,Khan Ramsha23ORCID,Kim Michael23,Brasseit Jennifer7,Cruz-Leal Yoelys123ORCID,Amash Alaa23ORCID,Kahlon Simrat23,Yougbare Issaka123ORCID,Ni Heyu12389ORCID,Zuercher Adrian W.7,Käsermann Fabian7ORCID,Semple John W.12348,Lazarus Alan H.12389ORCID

Affiliation:

1. Canadian Blood Services Centre for Innovation, Ottawa, Ontario K1G 4J5, Canada.

2. Department of Laboratory Medicine and Keenan Research Centre for Biomedical Science of St. Michael’s Hospital, University of Toronto, Toronto, Ontario M5B 1W8, Canada.

3. Toronto Platelet Immunobiology Group, Toronto, Ontario, M5B 1T8 Canada.

4. Department of Hematology and Transfusion Medicine, Lund University, Lund 221 84, Sweden.

5. Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, 1066 CX Amsterdam, Netherlands.

6. CSL Limited, Bio21 Institute, University of Melbourne, Parkville, Victoria 3010, Australia.

7. CSL Behring, Research, CSL Biologics Research Center, Bern, Switzerland.

8. Department of Medicine, St. Michael’s Hospital, University of Toronto, Toronto, Ontario M5B 1W8, Canada.

9. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

Abstract

An anti-erythrocyte antibody redirects inflammation in multiple mouse models.

Funder

The Canadian Blood Services

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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