Thrombopoietin receptor–independent stimulation of hematopoietic stem cells by eltrombopag-Reference-Cited by-同舟云学术

Thrombopoietin receptor–independent stimulation of hematopoietic stem cells by eltrombopag

Published:2018-09-12 Issue:458 Volume:10 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Kao Yun-Ruei¹^ORCID,Chen Jiahao¹,Narayanagari Swathi-Rao¹^ORCID,Todorova Tihomira I.¹^ORCID,Aivalioti Maria M.¹,Ferreira Mariana¹,Ramos Pedro M.²,Pallaud Celine²,Mantzaris Ioannis³⁴,Shastri Aditi³⁴,Bussel James B.⁵,Verma Amit³⁴⁶,Steidl Ulrich¹³⁴⁶⁷^ORCID,Will Britta¹⁴⁶⁷

Affiliation:

1. Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

2. Novartis Pharmaceuticals, Basel CH-4057, Switzerland.

3. Department of Oncology, Montefiore Medical Center, Bronx, NY 10467, USA.

4. Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10467, USA.

5. Pediatric Hematology/Oncology, Weill Cornell Medicine, New York, NY 10065, USA.

6. Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

7. Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

Abstract

Eltrombopag stimulates multilineage hematopoiesis through intracellular iron chelation.

Funder

National Cancer Institute

National Institute of Diabetes and Digestive and Kidney Diseases

New York State Department of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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