Neutrophils cause obstruction of eyelid sebaceous glands in inflammatory eye disease in mice-Reference-Cited by-同舟云学术

Neutrophils cause obstruction of eyelid sebaceous glands in inflammatory eye disease in mice

Published:2018-07-25 Issue:451 Volume:10 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Reyes Nancy J.¹,Yu Chen¹^ORCID,Mathew Rose¹,Kunnen Carolina M.²,Kalnitsky Joan¹,Redfern Rachel L.²,Leonardi Andrea³,Perez Victor L.¹,MacLeod Amanda S.⁴⁵,Gupta Preeya K.¹,Saban Daniel R.¹⁴

Affiliation:

1. Department of Ophthalmology, Duke Eye Center, Duke University School of Medicine, Durham, NC 27710, USA.

2. College of Optometry, The Ocular Surface Institute, University of Houston, Houston, TX 77204, USA.

3. Department of Neuroscience, Ophthalmology Unit, University of Padova, Padova 35128, Italy.

4. Department of Immunology, Duke University School of Medicine, Durham, NC 27710, USA.

5. Department of Dermatology, Duke University School of Medicine, Durham, NC 27710, USA.

Abstract

Neutrophils obstruct the meibomian gland in a mouse model of inflammatory eye disease and correlate with disease severity in patients with meibomian gland dysfunction.

Funder

National Eye Institute

National Institute of Allergy and Infectious Diseases

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Dermatology Foundation

Research to Prevent Blindness

Duke University

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference83 articles.