Antimalarial pantothenamide metabolites target acetyl–coenzyme A biosynthesis in Plasmodium falciparum-Reference-Cited by-同舟云学术

Antimalarial pantothenamide metabolites target acetyl–coenzyme A biosynthesis in Plasmodium falciparum

Published:2019-09-18 Issue:510 Volume:11 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Schalkwijk Joost¹^ORCID,Allman Erik L.²^ORCID,Jansen Patrick A. M.¹^ORCID,de Vries Laura E.³^ORCID,Verhoef Julie M. J.³,Jackowski Suzanne⁴,Botman Peter N. M.⁵,Beuckens-Schortinghuis Christien A.⁵^ORCID,Koolen Karin M. J.⁶^ORCID,Bolscher Judith M.⁶^ORCID,Vos Martijn W.⁶,Miller Karen⁴,Reeves Stacy A.⁴^ORCID,Pett Helmi³,Trevitt Graham⁷^ORCID,Wittlin Sergio⁸⁹,Scheurer Christian⁸⁹^ORCID,Sax Sibylle⁸⁹^ORCID,Fischli Christoph⁸⁹,Angulo-Barturen Iñigo¹⁰^ORCID,Jiménez-Diaz Mariá Belén¹⁰,Josling Gabrielle²^ORCID,Kooij Taco W. A.³^ORCID,Bonnert Roger¹¹,Campo Brice¹¹^ORCID,Blaauw Richard H.⁵,Rutjes Floris P. J. T.¹²^ORCID,Sauerwein Robert W.³⁶^ORCID,Llinás Manuel²¹³^ORCID,Hermkens Pedro H. H.¹⁴^ORCID,Dechering Koen J.⁶^ORCID

Affiliation:

1. Department of Dermatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.

2. Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, The Pennsylvania State University, University Park, PA 16802 USA.

3. Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.

4. St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

5. Chiralix, Nijmegen, Netherlands.

6. TropIQ Health Sciences, Nijmegen, Netherlands.

7. XenoGesis Ltd., Nottingham, UK.

8. Swiss Tropical and Public Health Institute, Basel, Switzerland.

9. University of Basel, Basel, Switzerland.

10. The Art of Discovery, Derio, Spain.

11. Medicines for Malaria Venture, Geneva, Switzerland.

12. Radboud University, Nijmegen, Netherlands.

13. Department of Chemistry, The Pennsylvania State University, University Park, PA 16802 USA.

14. Hermkens Pharma Consultancy, Oss, Netherlands.