Hematopoietic stem cell transplantation in immunocompetent hosts without radiation or chemotherapy-Reference-Cited by-同舟云学术

Hematopoietic stem cell transplantation in immunocompetent hosts without radiation or chemotherapy

Published:2016-08-10 Issue:351 Volume:8 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Chhabra Akanksha¹,Ring Aaron M.²³⁴,Weiskopf Kipp²³⁴,Schnorr Peter John¹,Gordon Sydney²³⁴,Le Alan C.¹,Kwon Hye-Sook¹,Ring Nan Guo²³⁴,Volkmer Jens²³⁴,Ho Po Yi²³⁴,Tseng Serena²³⁴,Weissman Irving L.²³⁴⁵,Shizuru Judith A.¹²³

Affiliation:

1. Blood and Marrow Transplantation, Stanford University School of Medicine, Stanford, CA 94305, USA.

2. Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

3. Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

4. Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

5. Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA.

Abstract

Combining anti–c-Kit antibodies with CD47 blockade depletes endogenous hematopoietic stem cells and enables bone marrow transplantation without radiation or chemotherapeutics.

Funder

Virginia and D.K. Ludwig Fund for Cancer Research

California Institute for Regenerative Medicine

NIH

Stanford Medical Scientist Training Program

Thomas and Stacey Siebel Foundation

Gunn/Olivier Research Fund

HL Snyder Medical Foundation

Stinehart-Reed Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject