Pediatric tri-tube valved conduits made from fibroblast-produced extracellular matrix evaluated over 52 weeks in growing lambs-Reference-Cited by-同舟云学术

Pediatric tri-tube valved conduits made from fibroblast-produced extracellular matrix evaluated over 52 weeks in growing lambs

Published:2021-03-17 Issue:585 Volume:13 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Syedain Zeeshan H.¹^ORCID,Haynie Bee,Johnson Sandra L.¹^ORCID,Lahti Matthew²,Berry James²,Carney John P.²^ORCID,Li Jirong³^ORCID,Hill Ryan C.⁴^ORCID,Hansen Kirk C.⁴^ORCID,Thrivikraman Greeshma¹^ORCID,Bianco Richard²,Tranquillo Robert T.¹⁵^ORCID

Affiliation:

1. Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA.

2. Experimental Surgical Services, University of Minnesota, Minneapolis, MN 55455, USA.

3. Department of Mechanical Engineering, University of Minnesota, Minneapolis, MN 55455, USA.

4. Department of Biochemistry and Molecular Genetics, University of Colorado–Anschutz Medical Campus, Aurora, CO 80045, USA.

5. Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455, USA.

Abstract

A pulmonary replacement valve made from three tubes of cell-derived matrix functioned for 52 weeks in lambs and calcified less than commercial valves.

Funder

NIH Office of the Director

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference36 articles.

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3. Current Interventional and Surgical Management of Congenital Heart Disease

4. Implantable arterial grafts from human fibroblasts and fibrin using a multi-graft pulsed flow-stretch bioreactor with noninvasive strength monitoring

5. Blood Outgrowth Endothelial Cells Alter Remodeling of Completely Biological Engineered Grafts Implanted into the Sheep Femoral Artery

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