Bimodal neuromodulation combining sound and tongue stimulation reduces tinnitus symptoms in a large randomized clinical study

Author:

Conlon Brendan123ORCID,Langguth Berthold45,Hamilton Caroline1ORCID,Hughes Stephen1ORCID,Meade Emma1ORCID,Connor Ciara O1ORCID,Schecklmann Martin45ORCID,Hall Deborah A.678ORCID,Vanneste Sven910ORCID,Leong Sook Ling110,Subramaniam Thavakumar3ORCID,D’Arcy Shona1,Lim Hubert H.11112ORCID

Affiliation:

1. Neuromod Devices Limited, Dublin D08 R2YP, Ireland.

2. School of Medicine, Trinity College, Dublin D02 R590, Ireland.

3. Department of Otolaryngology, St. James’s Hospital, Dublin D08 NHY1, Ireland.

4. Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg 93053, Germany.

5. Interdisciplinary Tinnitus Center of University of Regensburg, Regensburg 93053, Germany.

6. National Institute for Health Research Nottingham Biomedical Research Centre, Nottingham NG7 2UH, UK.

7. Hearing Sciences, Division of Clinical Neuroscience, University of Nottingham, Nottingham NG7 2RD, UK.

8. University of Nottingham Malaysia, Selangor 43500, Malaysia.

9. Lab for Clinical and Integrative Neuroscience, School of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, TX 75080, USA.

10. Global Brain Health Institute, Trinity College Dublin, Dublin D02 PN40, Ireland.

11. Department of Otolaryngology—Head and Neck Surgery, University of Minnesota, Minneapolis, MN 55455, USA.

12. Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA.

Abstract

Noninvasive bimodal neuromodulation reduces tinnitus symptom severity within 12 weeks of treatment for up to 12 months after completing treatment.

Funder

Neuormod Devices Limited

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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