A modified drug regimen clears active and dormant trypanosomes in mouse models of Chagas disease-Reference-Cited by-同舟云学术

A modified drug regimen clears active and dormant trypanosomes in mouse models of Chagas disease

Author:

Bustamante Juan M.¹^ORCID,Sanchez-Valdez Fernando¹²^ORCID,Padilla Angel M.¹^ORCID,White Brooke¹^ORCID,Wang Wei¹^ORCID,Tarleton Rick L.¹³^ORCID

Affiliation:

1. Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia, USA.

2. Instituto de Patología Experimental, Universidad Nacional de Salta-CONICET, Salta, Argentina.

3. Department of Cellular Biology, University of Georgia, Athens, Georgia, USA.

Abstract

A modified regimen of benznidazole prevents Trypanosoma cruzi dormancy-dependent treatment failure in several mouse models of Chagas disease.

Funder

National Institute of Allergy and Infectious Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference33 articles.

3. Chagas disease in Latin America: An epidemiological update based on 2010 estimates;WHO;Wkly. Epidemiol. Rec.,2015

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