A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes-Reference-Cited by-同舟云学术

A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes

Published:2021-06-02 Issue:596 Volume:13 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Wang Xi¹^ORCID,Maxwell Kristina G.²³^ORCID,Wang Kai⁴⁵^ORCID,Bowers Daniel T.¹^ORCID,Flanders James A.⁶^ORCID,Liu Wanjun¹^ORCID,Wang Long-Hai¹^ORCID,Liu Qingsheng¹,Liu Chengyang⁷^ORCID,Naji Ali⁷^ORCID,Wang Yong⁸,Wang Bo¹,Chen Jing¹^ORCID,Ernst Alexander U.¹^ORCID,Melero-Martin Juan M.⁴⁵⁹^ORCID,Millman Jeffrey R.²³^ORCID,Ma Minglin¹^ORCID

Affiliation:

1. Department of Biological and Environmental Engineering, Cornell University, Ithaca, NY 14853, USA.

2. Division of Endocrinology, Metabolism and Lipid Research, Washington University School of Medicine, St. Louis, MO 63110, USA.

3. Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.

4. Department of Cardiac Surgery, Boston Children’s Hospital, Boston, MA 02115, USA.

5. Department of Surgery, Harvard Medical School, Boston, MA 02115, USA.

6. Department of Clinical Sciences, Cornell University, Ithaca, NY 14853, USA.

7. Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.

8. Division of Transplant Surgery, University of Virginia, Charlottesville, VA 22904, USA.

9. Harvard Stem Cell Institute, Cambridge, MA 02138, USA.

Abstract

A nanofibrous cell encapsulation device containing rodent/human islets or human stem cell–derived β cells treats diabetes in rodents.

Funder

National Institutes of Health

National Institute of Diabetes and Digestive and Kidney Diseases

Hartwell Foundation

JDRF

Novo Nordisk Company

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference72 articles.

1. Navigating Two Roads to Glucose Normalization in Diabetes: Automated Insulin Delivery Devices and Cell Therapy

2. Pancreatic β Cell Regeneration as a Possible Therapy for Diabetes

3. International Trial of the Edmonton Protocol for Islet Transplantation

4. Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen

5. Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia

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