Fitness cost of antibiotic susceptibility during bacterial infection-Reference-Cited by-同舟云学术

Fitness cost of antibiotic susceptibility during bacterial infection

Published:2015-07-22 Issue:297 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Roux Damien¹²³,Danilchanka Olga⁴,Guillard Thomas¹⁵,Cattoir Vincent⁴⁶,Aschard Hugues⁷,Fu Yang⁴,Angoulvant Francois⁸,Messika Jonathan²,Ricard Jean-Damien²,Mekalanos John J.⁴,Lory Stephen⁴,Pier Gerald B.¹,Skurnik David¹

Affiliation:

1. Division of Infectious Diseases, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.

2. INSERM, IAME, UMR 1137, F-75018 Paris, France.

3. Université Paris Diderot, Sorbonne Paris Cité, F-75018 Paris, France.

4. Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.

5. EA 4687, Faculté de Médecine, Université de Reims Champagne-Ardenne, 51092 Reims, France.

6. EA 4655, Faculté de Médecine, Université de Caen Basse-Normandie, 14033 Caen, France.

7. Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.

8. Hôpitaux de Paris (AP-HP), Pédiatrique Emergency Département, Hôpital Necker-Enfants Malades and Université Paris Descartes, 75015 Paris, France.

Abstract

The quest to stem antibiotic resistance might be exacerbated by enhanced fitness and virulence displayed by the drug-resistant microbes.

Funder

U.S. National Institute of Allergy and Infectious Diseases

Cystic Fibrosis Foundation

AXA Research Fund

Societe de Reanimation de Langue Francaise

Seedlings Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference59 articles.

1. Antibiotic resistance and its cost: is it possible to reverse resistance?

2. A Comprehensive Analysis of In Vitro and In Vivo Genetic Fitness of Pseudomonas aeruginosa Using High-Throughput Sequencing of Transposon Libraries

3. Enhanced in vivo fitness of carbapenem-resistant oprD mutants of Pseudomonas aeruginosa revealed through high-throughput sequencing

4. Emergence of Antibiotic-Resistant Pseudomonas aeruginosa : Comparison of Risks Associated with Different Antipseudomonal Agents

5. Risk of emergence of Pseudomonas aeruginosa resistance to β-lactam antibiotics in intensive care units

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