Shaping mycolactone for therapeutic use against inflammatory disorders-Reference-Cited by-同舟云学术

Shaping mycolactone for therapeutic use against inflammatory disorders

Published:2015-05-27 Issue:289 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Guenin-Macé Laure¹²,Baron Ludivine¹²,Chany Anne-Caroline³,Tresse Cédric³,Saint-Auret Sarah³,Jönsson Friederike⁴⁵,Le Chevalier Fabien¹,Bruhns Pierre⁴⁵,Bismuth Georges⁶⁷⁸,Hidalgo-Lucas Sophie⁹,Bisson Jean-François⁹,Blanchard Nicolas³,Demangel Caroline¹²

Affiliation:

1. Institut Pasteur, Unité d’Immunobiologie de l’Infection, Paris 75015, France.

2. CNRS URA 1961, Paris 75015, France.

3. Université de Strasbourg, Laboratoire de Chimie Moléculaire, ECPM-CNRS UMR 7509, Strasbourg 67087, France.

4. Institut Pasteur, Unité Anticorps en Thérapie et Pathologie, Paris 75015, France.

5. INSERM U760, Paris 75015, France.

6. INSERM U1016, Institut Cochin, Paris 75014, France.

7. Université Paris Descartes, Paris 75014, France.

8. CNRS UMR 8104, Paris 75014, France.

9. ETAP, Inflammation, Dermatologie et Toxicologie, Vandœuvre-lès-Nancy 54500, France.

Abstract

A synthetic mycobacterial macrolide mycolactone decreases skin inflammation and inflammatory pain.

Funder

Fondation de la Recherche Medicale

Association Raoul Follereau

Region Ile de France

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference38 articles.

1. History, biology and chemistry of Mycobacterium ulcerans infections (Buruli ulcer disease)

2. Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans

3. Mycolactone: A Polyketide Toxin from Mycobacterium ulcerans Required for Virulence

4. Pathogenesis of skin ulcers: lessons from the Mycobacterium ulcerans and Leishmania spp. pathogens

5. Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation

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