The Constantly Changing Face of Chromatin-Reference-Cited by-同舟云学术

The Constantly Changing Face of Chromatin

Published:2003-04-09 Issue:14 Volume:2003 Page:
ISSN:1539-6150
Container-title:Science of Aging Knowledge Environment
language:en
Short-container-title:Sci. Aging Knowl. Environ.

Author:

Vaquero Alejandro¹,Loyola Alejandra¹,Reinberg Danny¹

Affiliation:

1. The authors are in the Howard Hughes Medical Institute, Division of Nucleic Acids Enzymology, Department of Biochemistry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA.(D.R.)

Abstract

Many recent findings have altered our vision of chromatin and its role in the regulation of cellular functions. Our perspective concerning chromatin has changed to a much more complex, but also more dynamic, view of chromatin as an entity that is intimately involved in the regulation of a variety of cellular functions. In this review, we describe the various types of proteins that alter the structure and, therefore, the function of chromatin and discuss the possible role of chromatin in cell aging. The elucidation of the mechanisms that link chromatin to aging will be one of the most exciting and striking advancements in the coming years

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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