Mitochondrial Bioenergetics, Aging, and Aging-Related Disease-Reference-Cited by-同舟云学术

Mitochondrial Bioenergetics, Aging, and Aging-Related Disease

Published:2002-08-07 Issue:31 Volume:2002 Page:
ISSN:1539-6150
Container-title:Science of Aging Knowledge Environment
language:en
Short-container-title:Sci. Aging Knowl. Environ.

Author:

Nicholls David¹

Affiliation:

1. The author is at the Buck Institute for Age Research, Novato, CA 94945, USA. E-mail: dnicholls@buckinstitute.org

Abstract

In this Perspective, the author discusses some of the bioenergetic consequences of the various alterations in mitochondrial function that have been hypothesized to be associated with human aging and aging-related disease. Special focus is afforded to neurodegenerative disease.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference19 articles.

1. D. G. Nicholls S. J. Ferguson Bioenergetics 3 (London Academic Press 2002).

2. M. D. Brand, Regulation analysis of energy metabolism. J. Exp. Biol. 200, 193-202 (1997).

3. Mitochondrial Diseases in Man and Mouse

4. T. P. Singer, R. R. Ramsay, Mechanism of the neurotoxicity of MPTP-an update. FEBS Lett. 274, 1-8 (1990).

5. Chronic systemic pesticide exposure reproduces features of Parkinson's disease

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