Adult neural stem cells have latent inflammatory potential that is kept suppressed by Tcf4 to facilitate adult neurogenesis

Author:

Shariq Mohammad12ORCID,Sahasrabuddhe Vinaya1,Krishna Sreevatsan1,Radha Swathi1,Nruthyathi 1ORCID,Bellampalli Ravishankara1,Dwivedi Anukriti1,Cheramangalam Rajit1,Reizis Boris3ORCID,Hébert Jean4,Ghosh Hiyaa S.1ORCID

Affiliation:

1. National Centre for Biological Science, Tata Institute of Fundamental Research (NCBS-TIFR), Bangalore, India.

2. The University of Trans-Disciplinary Health Sciences and Technology, Bangalore, India.

3. Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.

4. Departments of Neuroscience and Genetics, Albert Einstein College of Medicine, New York, NY, USA.

Abstract

Neural stem cells in the adult brain have inflammatory potential that is kept suppressed by psychiatric disease gene Tcf4.

Funder

Tata Insitute of Fundamental research

Ramanujan Fellowship

NCBS-TIFR, DAE, GoI

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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