RNA binding protein PCBP1 is an intracellular immune checkpoint for shaping T cell responses in cancer immunity-Reference-Cited by-同舟云学术

RNA binding protein PCBP1 is an intracellular immune checkpoint for shaping T cell responses in cancer immunity

Published:2020-05-29 Issue:22 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Ansa-Addo Ephraim A.¹²^ORCID,Huang Huai-Cheng¹³^ORCID,Riesenberg Brian¹²,Iamsawat Supinya¹,Borucki Davis¹^ORCID,Nelson Michelle H.¹^ORCID,Nam Jin Hyun⁴^ORCID,Chung Dongjun²⁴^ORCID,Paulos Chrystal M.¹^ORCID,Liu Bei¹^ORCID,Yu Xue-Zhong¹,Philpott Caroline⁵,Howe Philip H.⁶^ORCID,Li Zihai¹²^ORCID

Affiliation:

1. Department of Microbiology and Immunology and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA.

2. Pelotonia Institute for Immuno-Oncology and Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center-James, Columbus, OH 43210, USA.

3. National Taiwan University College of Medicine, Graduate Institute of Clinical Medicine, No.7 Chung San South Road, Taipei City 10002, Taiwan.

4. Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC 29425, USA.

5. Genetics and Metabolism Section, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Bethesda, MD 20892, USA.

6. Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29425, USA.

Abstract

RNA binding protein PCBP1 guards effector and antitumor T cell functions.

Funder

National Institutes of Health

American Cancer Society

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference58 articles.

1. Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential