Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy-Reference-Cited by-同舟云学术

Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy

Published:2021-04-23 Issue:17 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Chang Chunmei¹²^ORCID,Shi Xiaoshan¹²^ORCID,Jensen Liv E.¹²^ORCID,Yokom Adam L.¹²^ORCID,Fracchiolla Dorotea²³^ORCID,Martens Sascha²³^ORCID,Hurley James H.¹²^ORCID

Affiliation:

1. Department of Molecular and Cell Biology and California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA 94720, USA.

2. Aligning Science Across Parkinson’s Collaborative Research Network, Chevy Chase, MD 20185, USA.

3. Department of Biochemistry and Cell Biology, Max Perutz Labs, University of Vienna, Vienna BioCenter, Dr. Bohr-Gasse 9, 1030 Vienna, Austria.

Abstract

Reconstitution experiments show how different cargo receptors engage the autophagy machinery in unique ways to lipidate LC3.

Funder

National Institute of General Medical Sciences

Michael J. Fox Foundation for Parkinson’s Research

Human Frontier Science Program

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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