Extracellular vesicle–encapsulated IL-10 as novel nanotherapeutics against ischemic AKI-Reference-Cited by-同舟云学术

Extracellular vesicle–encapsulated IL-10 as novel nanotherapeutics against ischemic AKI

Published:2020-08-14 Issue:33 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Tang Tao-Tao¹^ORCID,Wang Bin¹^ORCID,Wu Min¹,Li Zuo-Lin¹,Feng Ye¹,Cao Jing-Yuan¹,Yin Di¹,Liu Hong¹,Tang Ri-Ning¹,Crowley Steven D.²,Lv Lin-Li¹^ORCID,Liu Bi-Cheng¹^ORCID

Affiliation:

1. Institute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.

2. Division of Nephrology, Department of Medicine, Duke University and Durham VA Medical Centers, Durham, NC, USA.

Abstract

Using extracellular vesicles for targeted delivery of IL-10 is an efficient therapeutic strategy against ischemic AKI.

Funder

National Natural Science Foundation of China

Major State Basic Research Development Program of China

National Key Research and Development Program of China Stem Cell and Translational Research

Clinic Research Center of Jiangsu Province

Postgraduate Research & Practice Innovation Program of Jiangsu Province

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference40 articles.

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4. Interleukin-10 inhibits ischemic and cisplatin-induced acute renal injury

5. Interleukin-10 deficiency aggravates kidney inflammation and fibrosis in the unilateral ureteral obstruction mouse model

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